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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RFC1
All Species:
26.67
Human Site:
T105
Identified Species:
53.33
UniProt:
P35251
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35251
NP_002904.3
1148
128255
T105
I
S
R
Q
D
P
V
T
Y
I
S
E
T
D
E
Chimpanzee
Pan troglodytes
XP_001140765
1148
128250
T105
I
S
R
Q
D
P
V
T
Y
I
S
E
T
D
E
Rhesus Macaque
Macaca mulatta
XP_001091287
1148
128475
T105
I
S
R
Q
D
P
V
T
Y
I
S
E
T
D
E
Dog
Lupus familis
XP_536259
1145
128125
T105
I
L
R
Q
D
P
V
T
Y
I
S
E
T
D
E
Cat
Felis silvestris
Mouse
Mus musculus
P35601
1131
125967
T104
V
S
Q
K
D
P
V
T
Y
V
S
E
T
D
E
Rat
Rattus norvegicus
NP_445999
1131
125770
T105
I
S
R
K
D
P
V
T
Y
I
S
E
T
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512744
1233
136122
T186
S
S
R
R
D
P
V
T
Y
V
S
E
T
D
E
Chicken
Gallus gallus
NP_001006456
1147
128454
V104
V
L
K
Q
H
P
V
V
Y
V
S
E
T
D
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35600
986
108596
E22
K
A
K
S
A
E
A
E
N
G
E
T
P
S
K
Honey Bee
Apis mellifera
XP_397246
911
103001
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797949
906
99249
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38630
861
94885
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.3
89.3
N.A.
82.4
81.3
N.A.
67.4
68.9
N.A.
N.A.
N.A.
39.9
36.2
N.A.
38
Protein Similarity:
100
99.6
98.5
93.7
N.A.
89.5
88.5
N.A.
77.2
79.6
N.A.
N.A.
N.A.
55.9
53.6
N.A.
52.2
P-Site Identity:
100
100
100
93.3
N.A.
73.3
93.3
N.A.
80
60
N.A.
N.A.
N.A.
0
0
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
93.3
80
N.A.
N.A.
N.A.
20
0
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
0
9
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
59
0
0
0
0
0
0
0
0
67
0
% D
% Glu:
0
0
0
0
0
9
0
9
0
0
9
67
0
0
67
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
42
0
0
0
0
0
0
0
0
42
0
0
0
0
0
% I
% Lys:
9
0
17
17
0
0
0
0
0
0
0
0
0
0
9
% K
% Leu:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
67
0
0
0
0
0
0
9
0
0
% P
% Gln:
0
0
9
42
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
50
9
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
50
0
9
0
0
0
0
0
0
67
0
0
9
0
% S
% Thr:
0
0
0
0
0
0
0
59
0
0
0
9
67
0
0
% T
% Val:
17
0
0
0
0
0
67
9
0
25
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
67
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _